Antiangiogenesis therapy in the treatment of metastatic colorectal cancer
نویسندگان
چکیده
منابع مشابه
Therapy for metastatic colorectal cancer.
Median overall survival of metastatic colorectal cancer patients treated with first- and second-line combination chemotherapy now extends to more than 20 months in some studies. Chemotherapy alone, particularly when oxaliplatin is included, may allow potentially curative resection of advanced disease. There is evidence that the addition of antibodies targeted against vascular endothelial growth...
متن کاملThe treatment of metastatic colorectal cancer.
Metastatic colorectal cancer represents an incurable condition, with the exception of a very select group of patients in whom surgical excision of recurrent disease is possible. Chemotherapy offers a significant palliative benefit and may prolong patient survival. The preferred cytotoxic agent is 5-fluorouracil, through the optimal administration schedule is unknown. Recent evidence also suppor...
متن کاملMultimodal treatment of metastatic colorectal cancer.
BACKGROUND Metastases to the liver is the leading cause of death in patients with colorectal cancer. METHODS The authors review the data on diagnosis and management of this clinical problem, and they discuss management options that can be considered. RESULTS Complete surgical resection of metastases from colorectal cancer that are localized to the liver results in 5-year survival rates rang...
متن کاملIndividualizing therapy for metastatic colorectal cancer.
Systemic therapeutic efficacy is central to determining the outcome of patients with metastatic colorectal cancer (CRC). In these patients, there is a critical need for predictive biomarkers to optimize efficacy whilst minimizing toxicity. The integration of a new generation of molecularly targeted drugs into the treatment of CRC, coupled with the development of sophisticated technologies for i...
متن کاملMaintenance therapy for metastatic colorectal cancer.
1444 www.thelancet.com/oncology Vol 16 November 2015 7 Blakely T, Shaw C, Atkinson J, Cunningham R, Sarfati D. Social inequalities or inequities in cancer incidence? Repeated census-cancer cohort studies, New Zealand 1981–1986 to 2001–2004. Cancer Causes Control 2011; 22: 1307–18. 8 Paltoo DN, Chu KC. Patterns in cancer incidence among American Indians/ Alaska Natives, United States, 1992–1999....
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ژورنال
عنوان ژورنال: Therapeutic Advances in Medical Oncology
سال: 2012
ISSN: 1758-8359,1758-8359
DOI: 10.1177/1758834012454464